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Dacikast Daclatasvir 60 mg Tablets

Dacikast Daclatasvir 60 mg (28tab.)

Manufacturer –  Natco Pharma Ltd.

Marketing – Aprazer health care pvt. Ltd.

The drug should always be used in combination with other drugs, for example:  ribavirin, Sofosbuvir, peg interferon. The course of treatment can last from 12 to 24 weeks and is set by the attending physician, depending on the characteristics of the disease in the patient.

If during the course of therapy with Daclatasvir there were side effects of 1 and 2 degrees of severity, you should continue taking the drug as usual. With complications of high severity or ineffectiveness of treatment, the course should be interrupted.

The medicine is better to take with food, drinking plenty of water. Take the drug daily, at the same time.

Side symptoms after the use of daclatasvir can be expressed in the form of:

  • insomnias;
  • headache;
  • migraines;
  • depressions;
  • irritabilities;
  • cramps;
  • nausea, vomiting;
  • diarrhea or constipation;
  • dry mouth, etc.

Dacikast Daclatasvir 60 mg (28tab.)

Manufacturer –  Natco Pharma Ltd.

Marketing – Aprazer health care pvt. Ltd.

The drug should always be used in combination with other drugs, for example:  ribavirin, Sofosbuvir, peg interferon. The course of treatment can last from 12 to 24 weeks and is set by the attending physician, depending on the characteristics of the disease in the patient.

If during the course of therapy with Daclatasvir there were side effects of 1 and 2 degrees of severity, you should continue taking the drug as usual. With complications of high severity or ineffectiveness of treatment, the course should be interrupted.

The medicine is better to take with food, drinking plenty of water. Take the drug daily, at the same time.

Side symptoms after the use of daclatasvir can be expressed in the form of:

  • insomnias;
  • headache;
  • migraines;
  • depressions;
  • irritabilities;
  • cramps;
  • nausea, vomiting;
  • diarrhea or constipation;
  • dry mouth, etc.

Antidote to the drug does not exist; the elimination of side effects by medical personnel is symptomatic.

Having started therapy with Daclatasvir, carefully monitor your health. Report any abnormalities or adverse events to your doctor.

  • Children and adolescents under 18 years;
  • During pregnancy;
  • In the period of breast-feeding;
  • in case of hypersensitivity to the active substance;
  • do not take in immunotherapy mode.

These groups of patients cannot be treated with Daclatasvir, as clinical trials for these groups have not been conducted.

Women of reproductive age should take the drug with caution, because at the moment the effect of Daclatasvir on reproductive function is not precisely established.

 

Daclatasvir

Daclatasvir is a modern antiviral agent that has the ability to inhibit the synthesis of specific protein NS5A by pathogens of chronic viral hepatitis C. the chemical compound Itself is not used in the treatment of this disease, but is used exclusively for the combined treatment of the liver in chronic viral hepatitis C (HCV). Original complex medicine, including daclatasvir, developed and manufactured under the trademark “Daklinza” from the US pharmaceutical company Bristol-Myers Squibb. One tablet of the drug contains 33 or 66 mg of daclatasvir dihydrochloride, in recalculation corresponds to 30 and 60 mg of daclatasvir.

 

How to use the substance daclatasvir?

Daclatasvir is indicated for use in combination with other anti-viral drugs and interferons. In official guidance on the use of “Dakosy” offered several treatment regimens for chronic HCV of different genotypes. Thus, for the treatment of hepatitis C of the first genotype, a combination of daclatasvir with asunaprevir, pegylated interferon and ribavirin is recommended, and for the treatment of hepatitis genotype 1b — a combination only with asunaprevir.

 

In addition to the original, in the market of pharmaceutical products in 2015 appeared means-generics with daclatasvir. These products are manufactured under license in the pharmaceutical factories of India, Egypt and several other countries (Dacikast, Daclahep, Natdac, DaciHep, Dactovin). However, it is impossible to buy generics with daclatasvir in pharmacies in Russia. The absence of generics in the free sale is due to the fact that the license agreement between Bristol-Myers Squibb and manufacturers of analogues provides for the restriction of sales of non-original means the list of countries specified in the Supplement to the license. Russia is not in this list, so officially generics in the Russian pharmaceutical market can not be implemented.

You can buy the necessary medicines on the websites of Indian or Egyptian pharmacies, which is, for obvious reasons, a risky event. A more convenient and safe option is to order medicines on our website, as we provide direct delivery of pharmaceutical products from India or Egypt.

Daclatasvir should be used with caution if the patient is diagnosed with cirrhosis.

Treatment with daclatasvir –

Indications for the use of daclatasvir are because of how it works the active compound. Daclatasvir blocks the formation of NS5A protein by the virus. As a result, the process of viral RNA replication, as well as the Assembly of viral particles, is disrupted. In order to avoid the adaptability of viruses to daclatasvir, it is used exclusively in combination with means of another mechanism of action (sofobuvir, ribavirin, peginterferon).

Daclatasvir release tablets. The composition of the original drug “Daklinza” includes the active compound of daclatasvir 30 mg or 60 mg. This tablet dosage, if necessary, allows increasing the daily dose of active substance 90 mg without disrupting the integrity of the pills. Description of the mechanism of action and features of the drug is set out in the annotation to it.

The course of treatment requires 3 packages (for 12-week therapy) or 6 packages (for 24-week therapy). In order not to buy a fake instead of the original, you need to have information about how the original tool looks. You can find it, go to the website of the manufacturer ” Daklinza ” and carefully studied the exterior of the pack.

To tablet to remain high quality, they must be properly stored. The package indicates that the room in which they are located, the temperature should not be higher than +30°C. the Patient should monitor the temperature in the room, especially in the summer. With its increase, the pharmacological properties of the active substance may change, which reduces its effectiveness and increases the likelihood of adverse reactions.

Daclatasvir side effects-

Side effects of daclatasvir in oral administration are rare. Possible side effects of this drug include:

  • insomnia, migraines, headaches;
  • irritability;
  • apathy, depression;
  • convulsion;
  • nausea, vomiting, diarrhea, constipation;
  • dry mouth;
  • muscle and joint pain;
  • allergic reaction.

While taking daclatasvir with other antiviral agents (sofosbuvir, ribavirin, peginterferon) side effects of each of them are enhanced. Therefore, when changing their health, patients should notify their doctor.

Since the likely adverse reactions from taking daclatasvir are not dangerous and rarely require discontinuation of the drug, there are few contraindications to its use. The tool is contraindicated in case of individual intolerance, under the age of 18 years, as well as women during pregnancy and breastfeeding. The use of the drug by children and women expecting or nursing children is limited for the reason that clinical studies of such patients have not been conducted.

Get more information about modern hepatitis C treatment-

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