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HEPCINAT LP ( SOFOSBUVIR 400MG & LEDIPASVIR 90MG )

The advantages of the application and effectiveness of Hepcinat LP

 

The contents

  1. Advantages Hepcinat LP Natco
  2. Differences Hepcinat LP
  3. Clinical efficacy
  4. Composition Hepcinat LP
  5. Indications for use
  6. application Circuit
  7. Contraindications
  8. Possible side effects
  9. Question about the authenticity and price of the drug
  10. Reviews of patients and physicians

 

For many years, in fact since its discovery, hepatitis C was considered incurable. Only now with the advent of antiviral drugs direct action patients in Russia and rest of the world, there is a serious possibility to get rid of this disease. Modern patterns of use of multiple drugs allow you to completely destroy the hepatitis C virus in human tissues. Pharmaceutical companies for patient convenience create dosage forms containing multiple active ingredients in one pill. One such Hepcinat lp.

Buy Hepcinat Lp Tablets Online Cost from India

The advantages of the application and effectiveness of Hepcinat LP

 

The contents

  1. Advantages Hepcinat LP Natco
  2. Differences Hepcinat LP
  3. Clinical efficacy
  4. Composition Hepcinat LP
  5. Indications for use
  6. application Circuit
  7. Contraindications
  8. Possible side effects
  9. Question about the authenticity and price of the drug
  10. Reviews of patients and physicians

For many years, in fact, since its discovery, hepatitis C was considered incurable. Only now with the advent of antiviral drugs direct action patients in Russia and rest of the world, there is a serious possibility to get rid of this disease. Modern patterns of use of multiple drugs allow you to completely destroy the hepatitis C virus in human tissues. Pharmaceutical companies for patient convenience create dosage forms containing multiple active ingredients in one pill. One such Hepcinat lp.

Advantages Hepcinat LP Natco

This drug produced the largest Indian pharmaceutical company “Natco Pharma“, made available to the medical community in 2015. It is a generic version of the original drug “HARVONI“.

The original tool was created in the United States and approved by medical Association as a treatment option completely eliminates chronic hepatitis C by stopping replication of the virus. However, like any new and original drug, it has a very high cost. Only a small number of patients can afford the full course of treatment with this drug.

The way out is treatment Hepcinat LP. Pharmaceutical company Natco LTD has acquired the rights to produce this combination of active substances, that is, all the essential stages of the synthesis are strictly observed.

Treatment Hepcinat LP efficiency is not different from the original treatment means. The cardinal feature is the price Hepcinat LP – the cost of the full course of therapy is 90 times less than when you receive “ HARVONI “.

This means that treatment with a direct antiviral action is available even for patients with little financial resources.

Differences Hepcinat LP

Many patients and doctors infectious profile are wondering what Hepcinat LP Natko different from Hepcinat, do the letters LP is an asset or not I should spend the extra Finance and can be purchased only Hepcinat LP

The difference lies not only in name but in composition. Hepcinat LP is a combined medicinal product that contains 2 active substances Ledipasvir and Sofosbuvir in the required therapeutic dosage. Normal Hepcinat is only Sofosbuvir, which as a means alone is not sufficient for the complete destruction of hepatitis C virus.

Clinical efficacy

Before treatment, hepatitis medicine Hepcinat LP it is useful to read some digital data, in order to fully appreciate all the features of this drug.

To 2013 patients suffering from chronic hepatitis C was receiving treatment of the so-called “gold standard” that included ribavirin and interferon. Long-term use (12, 24 and even 48 weeks) often cause multiple side effects which make treatment impossible. A major problem was the necessity of intramuscular injections of interferon, as performed shapes such plan drugs no.

In addition, the effectiveness of this therapy, too, left much to be desired – a stable and complete virologic response (SVR) was observed in less than 50% of patients, according to some – only 30-35%.

Generic analog Hepcinat LP reduces the viral load to zero in 95% of patients in the first month of use. After completion of the full course of therapy (12 sometimes 24 weeks) in 98% of cases hepatitis C virus in the blood of the patient is determined.

Triple therapy Hepcinat LP and Ribavirin in 100% of cases lead to the formation of SVR in patients with chronic hepatitis C.

Composition Hepcinat LP

Genuine Hepcinat LP available in tablets, which are coated with a special protective film. This is to ensure that the active substance did not start to disintegrate in the oral cavity and the esophageal tube, but only inside the stomach. This also eliminates irritating pills Hepcinat LP.

Drug Hepcinat LP contains 2 active ingredients:

  • Ledipasvir 90 mg;
  • Sofosbuvir 400 mg.

Excipients and components of the shell needed to create a stable main active ingredient.

Neither Sofosbuvir (for example, under the name Hepcinat ) or Ledipasvir cannot be used as a means of monotherapy in the treatment of chronic hepatitis C. the Strength of their action in combined use. In some cases, required the appointment of one antiviral agent and drugs medications.

Active ingredients Hepcinat LP obladaut complementary action. Sofosbuvir is an NS5B protease inhibitor, and ledipasvir – NS5A inhibits the enzyme. Their combined effect leaves the hepatitis C virus capabilities for replication, prevents the establishment of a number of daughter virions and genetically new samochody. Thus, multiplication of the pathogen is completely stopped and the illness is gone forever.

Indications for use

Hepcinat LP is administered to patients:

  • with HCV genotype 1;
  • hepatitis C genotype 4;
  • with compensated liver cirrhosis caused by hepatitis C virus;
  • previously treated the “gold standard”, but did not respond to treatment;
  • infected with HIV and hepatitis C.

There is a perception that Gazinet LP effective against hepatitis C genotype 5 and 6, but a serious evidence base is missing.

This drug is equally effective in genotype 1B, 1A, and 1B.

Application circuit

Instructions for use Hepcinat LP is intended for physicians, contains all the details of the use of the drug, takes into account all the possible combined use. Assign Hepcinat LP can only be a doctor.

The patient can see the most common patterns of use, but it is better to refrain from self-prescription of antiviral drugs direct action.

Hepcinat LP can be administered in such schemes:

 

    Category of patients

 

    Other antiviral drugs

 

        Duration of use

 

Persons who did not receive treatment and receive earlier therapy, “gold standard”

 

with genotype 1

 

 

 

 

 

12 weeks

 

Persons who did not receive treatment and receive earlier therapy, “gold standard”

 

with genotype 4

 

 

Ribavirin

 

 

12 weeks

 

Patients with compensated and subcompencirovanna cirrhosis of the liver

 

24 weeks

 

Patients with HIV and hepatitis C genotype 1

 

12 weeks

Statistics of recovery are evaluated after completion of treatment using standard serological and biochemical reactions.

The patient during the entire course of therapy should take 1 pill Hepcinat LP without chewing or be crushing it. The drug combination with a small amount of regular drinking (non-carbonated) water. No matter the meal, Hepcinat LP can be taken before him or after him. All the doctors strongly recommended taking this medicine at the same time.

The composition of Hepcinat LP eliminates the opportunity to take alcohol.

Contraindications

There are situations when active ingredients Hepcinat LP can harm a person or not produce the desired effect.

  • This medicinal product is contraindicated:
  • persons that are allergic to Ledipasvir or Sofosbuvir;
  • patients under 18 years of age;
  • pregnant women of any age, and nursing;
  • persons of both sexes who are planning conception (possible genetic anomalies);
  • patients with decompensated cirrhosis;
  • persons with ascites and encephalopathy yavleniyami;
  • patients infected with another hepatitis virus (b, D, etc.).

It is undesirable to take this antiviral agent with phenytoin, carbamazepine, St. John’s wort, remedies, lowering cholesterol. The attending physician will individually solve a question on the necessity of reception of a means, and the suspension of another.

Possible side effects

Side effects on the background of the application of Hepcinat LP are observed infrequently. All cases of change of the own state need to inform the doctor. The composition of Hepcinat LP may provoke:

  • pain in the head;
  • General fatigue and lack of energy;
  • a decrease in vision clarity and concentration;
  • nausea, sometimes vomiting;
  • muscle weakness.

Special caution should be observed patients receiving enalapril and lisinopril because of the possible development of bradycardia.

Individuals receiving triple therapy (with ribavirin), need for regular blood General clinical analysis of blood since it is possible a significant reduction of hemoglobin. If this indicator drops to the lower critical level, the Ribavirin should be discontinued.

Throughout the course of antiviral therapy, patients should use reliable contraception. Oral contraceptives do not affect the efficiency of Hepcinat LP.

The question of the authenticity and price of the drug

In Russia the patient buying Hepcinat LP on the Internet platform, often the question arises, how to distinguish a fake Hepcinat LP from this drug. Do effective drug Buy Hepcinat LP from India is distinguished by the following points:

  • clearly identify the batch number, production date, and shelf life;
  • special NDC code on the package;
  • concentric circles on the packaging and the red hologram on the box lid;
  • greenish-blue color tablets;
  • instruction Hepcinat LP in English.

All this allows to verify the authenticity of the composition of the drug for a few minutes and to refrain from buying questionable quality.

The cost of packaging a genuine means for 28 tablets is approximate 240$

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