Hepcvir (Sofosbuvir)+Hepcdac (Daclatasvir) (1,2,3,4 genotype in combination) (Cipla Ltd )
International nonproprietary name Sofosbuvir + daclatasvir .
Hepcvir (Sofosbuvir) accessible in tablets square measure pink in color, ovoid in form with a marked on one facet in Arabic numerals: “SF 400”, that corresponds to the content of the active substance (Sofosbuvir) in AN quantity of four hundred mg.
Hepcdac (daclatasvir) accessible in tablets around the odds of inexperienced at sixty mg.
The antiviral agent directed action – the drug doesn’t act with the healthy cells of the liver. This happens as a result of the medication solely applies to “tools” (enzymes), viral hepatitis virus, within which every genotype is building its own chain of nucleic acids. 1st is that the method of destruction of the nucleus of liver cells by cutting the DNA chain into fragments, then use the polymer-enzyme is “stitching” your own thread virus polymer.
Sofosbuvir inhibits infective agent polymer-enzyme, thereby not permitting the virus to multiply. Active against genotypes of hepatitis C: one,2,3 and four sorts.
daclatasvir blocks the catalyst 5B (NS5В), depriving one,2,3,4,5,6 styles of liver disease viruses With a primary weapon, that destroyed the nucleus of liver cells (cut chains of nucleotides).
Sofosbuvir and daclatasvir used for the treatment of acute and chronic hepatitis: one, 2, 3,4, 5, six genotypes of viral hepatitis virus.
Is used pathology and cirrhosis of the liver of the liver, related to lesions on all genotypes of hepatitis C.
Required eighty-four pill of sofosbuvir and daclatasvir a course of treatment in uncomplicated kind of the malady (12 weeks). At the onset of cirrhosis of the liver of the liver, treatment is redoubled to twenty-four weeks.
The drug is contraindicated in maternity and lactation and in kids up to eighteen years. don’t use if you’re sensitized to any of the ingredients: Hepcvir (Sofosbuvir) and Hepcdac (Daclatasvir)
Changes in the composition of peripheral blood: the decrease in the variety of erythrocytes, lymphocytes, leukocytes, and platelets.
The redoubled sensitivity of the skin.
During the reception drug isn’t counseled to sun on the beach or within the sun parlor, as owing to the redoubled sensitivity of the skin could expertise sunburn.
While the applying reduces the contraceptive impact of oral contraceptives, that embrace preparations of sex hormone. throughout treatment, it’s counseled to use a further reliable methodology of birth prevention.
Enhances the impact of antiarrhythmic drug, nifedipine, lidocaine, warfarin, thereby increasing the danger of cardiac arrhythmia and prevalence of hurt.
The terms of the acquisition
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