MyHep Sofosbuvir 400 mg (Sofosbuvir) is included in the group of potent nucleotide inhibitors that block the production of RNA in the virus protein NS5A (provokes the development of diseases hepatitis C).
The main goal of the medication – reducing the spread of the virus through the circulatory system; protects liver cells and restores the functionality of this important body. The drug does not need the additional intake of protein, developing the immunity of the immunity to the virus naturally.
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Among modern preparations of directed action for the treatment of chronic hepatitis, C Sofosbuvir relate to innovative medicines, as it can appoint additional use of interferon.
The active ingredient of the drug has a depressant effect on the reproduction of RNA-containing virus is hepatitis C, it can partially or completely block the synthesis of NS5B protein. Sofosbuvir relate to the so-called Pro-drugs. Inhibitory effect substance manifests only when injected into the blood through a mass of complex chemical transformations at the molecular level. The maximum concentration of sofosbuvir 400 mg when injected into the body lasts more than a day, so taking the drug just once a day.
Method of application and doses :
Tablets are coated, so to crack them or chew is not recommended due to bitter taste. Take the medicine during the meal. If the drug was having to vomit and it took less than 2 hours, the reception should be repeated. If after taking the medication it took more than two hours, repeated administration of the medicine is not needed.
If you skip taking with a delay of fewer than 18 hours, the drug is taken, and the following method is carried out at the usual time. If the medication pass is more than 18 hours before the next pill is taken at the usual time.
Among the side effects described:
• a headache, migraine;
• Irritability, insomnia, fatigue;
• disorders of the gastrointestinal tract;
• rashes, itching of the skin;
• pain in the joints, myalgia;
• changes in the composition of the blood;
• blurred vision;
• a cough, nasopharyngitis and other manifestations.
Not recommended medication if you are hypersensitive to its components.
Sofosbuvir is not prescribed to pregnant and women during lactation.
The effect of the drug on the reproductive function have not been described. But you should avoid pregnancy while taking the drug. Especially in the combination of Sofosbuvir with other antiviral drugs.
There is no data on the effectiveness of the safe use of medications in the treatment of patients up to 18 years.
Interaction with other drugs
Depending on the genotype of hepatitis C virus are assigned different combinations of medicines:
• 4,5,6 genotype Sofosbuvir with interferon and ribavirin for 12 weeks;
• 1,4,5,6 genotype (for patients intolerant to interferon) – Sofosbuvir with ribavirin, a rate of more than 24 weeks;
• Genotype 2 – Sofosbuvir with ribavirin, a rate of more than 12 weeks;
• Genotype 3 – Sofosbuvir with ribavirin and interferon alpha, the rate of more than 12 weeks.
Sofosbuvir with ribavirin is administered to patients who are preparing for transplantation of the liver. The same scheme is applicable for the treatment of joint infection of hepatitis C and HIV.
Other regimens with antiviral drugs prescribed in the absence of strong side effects in the appointment of a complex of antiviral drugs.
Keep the preparation at temperature from 15 °C to 30 °C