Sorafenat is the latest drug, multikinase inhibitor having antitumor action.
The active substance is sorafenib tosylate tablets has an inhibitory effect on tumor growth. Sorafenat is used in the treatment of metastatic renal cell and hepatocellular carcinoma. Studies have established the effectiveness of the drug, Sorafenat able to reduce the risks of further progression of the disease when such diagnoses as primary liver cancer or hepatocellular carcinoma. You can Buy Sorafenat Sorafenib 200mg from India and also you can check online price of the sorafenat tablet. The drug is used in more than 100 countries. Use of sorafenat 200 mg is also important as a replacement therapy with interferon-alpha and interleukin those patients in whom this treatment due to various factors contraindicated or not help. Use of Sorafenat possible and as 1st-line therapy for inoperable and locally advanced disseminated and metastatic kidney cancer, as well as 2nd line treatment for reset location kidney cancer and tumors, and immune cytokines.
sorafenib natco usage instructions
The testimony of the drug:
– metastatic renal cell cancer;
– hepatocellular carcinoma
Method of application:
Inside. The recommended dose of 800 mg/day. To carry out reception it is possible and Sorafenat on an empty stomach and with food. It is desirable that the food does not contain large amounts of fat because it reduces the bioavailability of sorafenib, 200 mg tab price is very low.
Sorafenat stop treatment in case of clinical effect.
The drug should be discontinued if the treatment occurs Sorafenat unacceptable toxic effects.
Dose reduction to 400 mg/day may be required in the event of various side effects.
No data on the use of Sorafenat in patients with impaired liver function severe and in patients who are on hemodialysis.
Treatment Sorafenat is performed under the supervision of a physician, who has experience of antitumor therapy.
During the course of taking Sorafenat, you want to observe the peripheral blood (WBC and platelets).
Most often side effects while taking SorafenatSorafenat, appropriate treatment. The repeated repetition of the data of side effects, and if severe manifestations, treatment with sorafenib could not be continued.
During the course of taking Sorafenat, you should regularly monitor the blood pressure of the patient to prevent the development of hypertension. When it is necessary to prescribe antihypertensive drugs. With the development of severe or resistant hypertension a possible withdrawal of the drug.
When assigning Sorafenat in combination with warfarin should be regularly to determine prothrombin time, INR and clinical signs of bleeding.
For appointment or resumption of therapy with the use Sorafenat in the case of surgical interventions requires a special solution which should be based on the assessment of the adequacy of wound healing.
Therapy with the use of Sorafenat can be stopped if signs of ischemia and/or myocardial infarction, perforation of the gastrointestinal tract.
Sorafenat should be used with caution in combination with drugs that are metabolized/excreted mainly with the participation of UGT1A1 (irinotecan), and also with docetaxel.
In patients with risk of renal dysfunction is necessary to conduct monitoring of water and electrolyte balance.